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Radhika Basheer, PhD

Radhika Basheer, PhD

Associate Professor

Research Roles/Affiliations

Department of Psychiatry, Harvard Medical School

Research Health Scientist and Director, Molecular Division,

Laboratory of Neuroscience, Psychiatry Research at VA Boston Healthcare System

Contact Information

1400 V.F.W. Parkway, Bldg 3, Rm 2A101, West Roxbury, MA

Phone: 617-699-6152

E-mail: Radhika_Basheer@hms.harvard.eduRadhika.Basheer@va.gov

Research

Basheer lab research focuses on the molecular, cellular and biochemical regulation of sleep, sleep homeostasis.  and state- associated cortical oscillations. Her approach includes genetics, in vivo electrophysiology, neuroanatomical and neurochemical techniques, including the cutting-edge methodologies of CRISPR-Cas9 gene editing and endoscopic calcium imaging to assess neuronal activity in vivo. The specific objective is identify molecular targets for pharmacological interventions as well as to understand the functional interaction of multiple neuronal subtypes in the onset and maintenance of behavioral states. Currently her work is focused on the role of basal forebrain and thalamic structures in the regulation of sleep and wakefulness and sleep-wake-associated cortical oscillations.

Research Interests

Sleep neurobiology

Effect of time restricted feeding on sleep

Gap-junction proteins in sleep

Neuronal circuitry of sleep-wake behavior

Grants

VA Biomedical Laboratory Research and Development Service Merit Award I01 BX001404

NIH R01 NS119227

NIH R21 NS